Impact of Elective Percutaneous Transluminal Coronary Angioplasty (PTCA) on Heart Rate Variability in Patients with Coronary Artery Disease
Keywords:Coronary artery disease, heart rate variability, PTCA
Coronary artery disease (CAD) is a major public health problem in India and is one of the leading causes of
mortality and morbidity. Impairment of heart rate variability (HRV) has been observed in patients with CAD.
Percutaneous transluminal coronary angioplasty (PTCA) is one of the common modalities of treatment of
CAD. In this study we have studied the effect of successful elective PTCA on HRV parameters in patients
Material and Method: HRV parameters in both time and frequency domain were studied in 30 male patients
before PTCA, one day and three day after PTCA.
Results: - The time and frequency domain parameters between pre PTCA and 1st day post PTCA were
not found to be statistically significant. Changes in the time domain parameter rMSSD and SDNN was
statistically significant between pre and 3rd day post PTCA but no significant difference was observed in
pNN50. A significant decrease in LF n.u and increase in HF n.u was observed between pre and 3rd day post
Conclusion: Revascularization with PTCA results in improvement of the autonomic tone. Improved
autonomic modulation is seen as early as 3rd day post PTCA. It indicates that restoring the blood flow
reverses to some extent the autonomic modulatory effect of coronary artery disease.
How to Cite
. Copyright Policy
Authors who publish with this journal agree to the following terms:-
-Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.
-Authors continue to retain publishing rights to the article without restrictions.