Impact of Elective Percutaneous Transluminal Coronary Angioplasty (PTCA) on Heart Rate Variability in Patients with Coronary Artery Disease

Authors

  • Anahita R. Shenoy Basti1, Venkatesh D.2 , V. S. Prakash2

DOI:

https://doi.org/10.37506/ijop.v8i3.1322

Keywords:

Coronary artery disease, heart rate variability, PTCA

Abstract

Coronary artery disease (CAD) is a major public health problem in India and is one of the leading causes of

mortality and morbidity. Impairment of heart rate variability (HRV) has been observed in patients with CAD.

Percutaneous transluminal coronary angioplasty (PTCA) is one of the common modalities of treatment of

CAD. In this study we have studied the effect of successful elective PTCA on HRV parameters in patients

with CAD.

Material and Method: HRV parameters in both time and frequency domain were studied in 30 male patients

before PTCA, one day and three day after PTCA.

Results: - The time and frequency domain parameters between pre PTCA and 1st day post PTCA were

not found to be statistically significant. Changes in the time domain parameter rMSSD and SDNN was

statistically significant between pre and 3rd day post PTCA but no significant difference was observed in

pNN50. A significant decrease in LF n.u and increase in HF n.u was observed between pre and 3rd day post

PTCA.

Conclusion: Revascularization with PTCA results in improvement of the autonomic tone. Improved

autonomic modulation is seen as early as 3rd day post PTCA. It indicates that restoring the blood flow

reverses to some extent the autonomic modulatory effect of coronary artery disease.

Author Biography

Anahita R. Shenoy Basti1, Venkatesh D.2 , V. S. Prakash2

1Assistant Professor, Department of Physiology, Father Muller Medical College, Mangalore-575002, India, 2 Professor, Department of Physiology, M.S. Ramaiah Medical College, Bangalore-560054, India

Published

2020-07-22

How to Cite

Anahita R. Shenoy Basti1, Venkatesh D.2 , V. S. Prakash2. (2020). Impact of Elective Percutaneous Transluminal Coronary Angioplasty (PTCA) on Heart Rate Variability in Patients with Coronary Artery Disease. International Journal of Physiology, 8(3), 12-16. https://doi.org/10.37506/ijop.v8i3.1322