Comparative Study of Sympathetic Activity in Normotensive Obese and Nonobese Adults


  • Syeda Samina1 , Mohammed Mazhar ul Haque2



Normotensive Obese, Cold pressor test, sympathetic activity, Diastolic blood pressure.


Aim: The aim of the study is to assess sympathetic activity in Obese Normotensive subjects

Objectives: To investigate any changes in sympathetic activity in Normotensive obese subjects using Cold

Pressor test

Method: 50 Obese subjects of both genders between age group 18-25 years with BMI>25kg/m2 were

selected as study group and 50 age matched subjects of both the genders with BMI<25Kg/m2 were selected

as control group. Sympathetic activity was assessed using Cold pressor test. In this test, After recording

the resting blood pressure (BP), the subject was asked to immerse his hand in cold water (temperature

maintained between 5°–9°C). BP measurement from other arm was done at 30 sec interval for two minutes

using continuous ambulatory Blood pressure monitoring, after which the subject was asked to remove the

hand from cold water. Maximum increase in Diastolic Blood Pressure (DBP) was taken as test response.

Results: Statistical analysis was done using unpaired t test.Increase in diastolic blood pressure with Cold

pressor test in study group was significantly increased compared to control group.

Conclusion: Increased sympathetic activity is seen in obese normotensive subjects,which is a risk factor

for future development of hypertension and other complications associated with increased sympathetic

activity.weight loss and maintanence of healthy lifestyle is suggested to the subjects to prevent the future


Author Biography

Syeda Samina1 , Mohammed Mazhar ul Haque2

1Assistant Professor of Physiology, Great Eastern Medical School & Hospital, Ragolu, Srikakulam, Andhra

Pradesh, 2Professor of Anaesthesia, Patnam Mahender Reddy Institute of Medical Sciences, Chevella, Telangana



How to Cite

Syeda Samina1 , Mohammed Mazhar ul Haque2. (2020). Comparative Study of Sympathetic Activity in Normotensive Obese and Nonobese Adults. International Journal of Physiology, 8(3), 98-101.