Effect of Acute Warm Water Swim Stress on Antioxidant Levels in Swiss Albino Rats
Keywords:Antioxidant, stress, warm water
Background: Heat stress affects both physical and mental tasks. Imbalance in maintenance of temperature
leads to oxidative stress and damage to the body systems. Aim: To evaluate the effect of acute warm water
swim stress on antioxidant status changes in albino rats. Materials and Methods: The present study was
conducted in the Department of Physiology, Meenakshi medical College& Research Institute, Chennai.
Twenty male albino rats were randomly divided in to two groups, control group and experimental group.
Experimental group of rats were exposed to warm water swim stress at 40ºc for duration of 15min of
continuous single exposure. The antioxidant status namely enzyme activity (LPO,CAT, SOD & GPx) and
non-enzyme activity (Vitamin C & Vitamin E) were estimated as per standard procedures. Results: There
was a significant (P<0.001) increase in Lipid peroxidation and was significantly (P<0.001) decrease in
enzyme activity (SOD, CAT, & GPx) and non- enzyme activity (Vitamin C & Vitamin E) when compared
with their normal controls. Conclusion: The changes in antioxidant estimation helps in developing a new
approach in understanding the changes in the body under acute exposure to heat water swim stress which
is mainly responsible for pathophysiological changes and to know the thermoregulatory activities of the
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