Effect of Acute Warm Water Swim Stress on Antioxidant Levels in Swiss Albino Rats

Authors

  • B.A. Madhuri
  • Rajeswar Reddy

DOI:

https://doi.org/10.37506/ijop.v9i1.2604

Keywords:

Antioxidant, stress, warm water

Abstract

Background: Heat stress affects both physical and mental tasks. Imbalance in maintenance of temperature
leads to oxidative stress and damage to the body systems. Aim: To evaluate the effect of acute warm water
swim stress on antioxidant status changes in albino rats. Materials and Methods: The present study was
conducted in the Department of Physiology, Meenakshi medical College& Research Institute, Chennai.
Twenty male albino rats were randomly divided in to two groups, control group and experimental group.
Experimental group of rats were exposed to warm water swim stress at 40ºc for duration of 15min of
continuous single exposure. The antioxidant status namely enzyme activity (LPO,CAT, SOD & GPx) and
non-enzyme activity (Vitamin C & Vitamin E) were estimated as per standard procedures. Results: There
was a significant (P<0.001) increase in Lipid peroxidation and was significantly (P<0.001) decrease in
enzyme activity (SOD, CAT, & GPx) and non- enzyme activity (Vitamin C & Vitamin E) when compared
with their normal controls. Conclusion: The changes in antioxidant estimation helps in developing a new
approach in understanding the changes in the body under acute exposure to heat water swim stress which
is mainly responsible for pathophysiological changes and to know the thermoregulatory activities of the
mammals.

Author Biographies

B.A. Madhuri

Assistant Professor, Department of Physiology, RVM Institute of Medical Sciences and
Research Center, Mulugu, Laxmakkapally, Telangana

Rajeswar Reddy

Associate Professor, Department of Physiology, RVM Institute of Medical Sciences and
Research Center, Mulugu, Laxmakkapally, Telangana

Published

2021-02-02

How to Cite

Madhuri, B., & Reddy, R. . (2021). Effect of Acute Warm Water Swim Stress on Antioxidant Levels in Swiss Albino Rats. International Journal of Physiology, 9(1), 7-10. https://doi.org/10.37506/ijop.v9i1.2604