Survival Patterns of Hormone Refractory Prostate Cancer in Sulaymaniyah, Iraqi Kurdistan
Keywords:Prostate cancer, survival patterns, adenocarcinoma.
As the most common solid tumor diagnosed among men, prostate cancer is responsible for the death of a
remarkable number of men worldwide every year. The present study was carried out in order to figure out
the survival patterns and the effective variables in patients with hormone refractory prostate cancer. Using
a retrospective cohort design with a nested case-control study approach, the present study was carried out
on 150 patients with prostate cancer at Hiwa Cancer Hospital located in Sulaimania, the Iraqi Kurdistan
in 2014. The patients were assigned into a case group (who developed resistance to androgen deprivation
therapy) and a control group (who did not develop resistance to androgen deprivation therapy within the first
three years of prostate cancer treatment). The required data were collected through a researcher-designed
questionnaire and using the patients’ hospital records. Most of the patients aged between 65 to 80 years.
According to the results, the highest survival probability belonged to the age group 60-80, while the lowest
was related to those aged less than 60 years, and there was no significant relationship between age groups
and overall survival (p>0.05). Prostate cancer is more likely to develop in males aged 65 to 80 year. They
patients’ overall survival is not correlated with their age, while there is a correlation between the stage
of their tumors and their overall survival. The patients’ their progression-free survival was found to be
significantly affected by their age and histopathology, while the stage of their tumors was not in a significant
correlation with their progression-free survival.