The Effect of Abuse of Some Anabolic Steroids on Hormonal and Testicular Function in Male Rats
Keywords:Anabolic androgenic steroids, testosterone, prolactin
Anabolic androgenic steroids are complex molecules contain innate male hormone, the prolonged uses of
these molecule cause destructive effects on health, thus, the investigation goals of this study to clarify the
effect of high doses of anabolic steroids on follicle stimulating hormone (FSH), luteinizing hormone (LH),),
testosterone hormone, prolactin and estrogen hormones levels, sperm parameters (sperm count, motility,
abnormality and viability), also to clarify the effect on body ,Epididymis and test weight. This study was
carried out by treating rats with a high doses of anabolic steroids (testosterone and nandrolone) hormones.
After 35 days of treatment ,the result indicated that ,there was a significant decrease in FSH,LH and
testosterone hormones level while prolactin and estrogen will be increased, Although there was a significant
decrease in sperm count ,motility and viability while abnormality will be increased ,body and test weight
show statistically decrease.