Effect of Brown Algae Extract Sargassum sp on Malondialdehyde Levels in White Rats (Rattus Norvegicus) Pregnant Wistar Strains
Keywords:Sargassum sp, Malondialdehyde, Rattus norvegicus.
Pregnancy is an inflammatory condition that produces unstable oxidative stress and can damage
macroeconomic tissue including DNA and protein which disrupt the placentation process. Increased levels
of malondialdehyde as an indicator of lipid peroxidation and decreased levels of antioxidants. This research
was conducted experimentally with pretest-posttest Control Group Design. Using three treatment groups
for the white rat (Rattus Norvegicus) test for Pregnant Wistar Strains. Twenty-one samples consisted of
three groups (Group 1 negative control, Group 2: sea algae extract Sargassum sp dose 300 mg/kg bb/day,
Group 3: sea algae extract Sargassum sp dose 600 mg/kg bb/day. Malondialdehyde levels were determined
by examination Eliza sandwich The results showed that Sargassum Sp brown algae extract had a significant
effect on decreasing levels of malondialdehyde (300mg p: 0.008 dose; 600mg p: 0.001 dose) in white rats
(Rattus norvegicus) Pregnant Wistar Strains.