Preparation & Characterization of Some Poly Ester-Amide as Drug Polymers

Authors

  • Abeer Abdul RazakMohammed1 ; ManalAzat Aziz2

DOI:

https://doi.org/10.37506/mlu.v20i3.1558

Keywords:

lactide ; aminoacid ; biodegradable ; polymeric drugs

Abstract

In this research,lactide was synthesized by ring opening polymerization then reacted with amino

acid to obtain drug polymer,poly (ester-amide)by condensation polymerization at 90C?with mixture

DMF&dioxane(1:1),then the biodegradable polymers substituted by some hydroxyl drug units such as

3-hydroxy pyridine .The action of polymeric drugs depends on hydrolytic & cleavage of the drug moiety

from the polymer,this give advantage of late & sustained release of drug over long time with decrease of

side effects .The new polymers wich has bioactive group’s moiety were measured physical properties and

characterized by FTIR & UV spectroscopy and TG thermogram.

Author Biography

Abeer Abdul RazakMohammed1 ; ManalAzat Aziz2

1 University of Mustanseriya , College of Science, Department of Chemistry;

2 Al-Mansour Institution of Medical Technology Middle Technical University

Published

2020-07-24

How to Cite

Abeer Abdul RazakMohammed1 ; ManalAzat Aziz2. (2020). Preparation & Characterization of Some Poly Ester-Amide as Drug Polymers. Medico Legal Update, 20(3), 1159-1164. https://doi.org/10.37506/mlu.v20i3.1558