Helicobacter Pylori-Associated Iron-Deficiency Anemia and Interleukins Effect

Authors

  • AthraaRazaq Mohammed Hindi1 , Oday MitibHadi2

DOI:

https://doi.org/10.37506/mlu.v21i1.2292

Keywords:

Helicobacter pylori, iron deficiency anemia, interleukins

Abstract

Helicobacter pylori (H. pylori) is a highly prevalence microbial infection, that acts as an iron stressor in
susceptible individuals the relationship between ferritin and cytokine levels in individuals infected with H.
pylori remains controversial. Based on serology testing for anti-H. pylori IgG, participants (70 seropositive
and 70 seronegative aged 30-60 years were enrolled. Serum iron profiles including iron, ferritin, and total
iron-binding capacity, were measured. IL-1? and IL-6 serum levels were compared. The mean value of
interleukin 1beta (IL-1?) level of patients and controls revealed that H. pylori patients had a significantly
higher at (P< 0.001) mean of (IL-1?) when compared to the controls, as shown in this study there is positive
correlation between gastric interleukin 1beta (IL-1?) and iron deficiency anemia (IDA) blood parameters
observed in resent study could be due to the powerful capability of IL-1? in inhibiting gastric acid secretion.
The mean value of Interleukin-6 (IL-6)) level of patients and controls revealed that H. pylori patients had a
significantly higher at (P< 0.001) mean of (IL-6) when compared to the controls.

Author Biography

AthraaRazaq Mohammed Hindi1 , Oday MitibHadi2

1
Research Scholar, College of Health and Medical Techniques, Al-Furat Al-Awsat Technical University, Al-Najaf,
Al-Kufa, Iraq, 2
Professor, Corresponding Author, College of Health and Medical Techniques, Al-Furat Al-Awsat
Technical University, Al-Najaf, Al-Kufa, Iraq

Published

2021-01-09

How to Cite

AthraaRazaq Mohammed Hindi1 , Oday MitibHadi2. (2021). Helicobacter Pylori-Associated Iron-Deficiency Anemia and Interleukins Effect. Medico Legal Update, 21(1), 125-128. https://doi.org/10.37506/mlu.v21i1.2292