Saliva of Tobacco Smokers a Profile of C3, IgA, Amylase and Total protein
Keywords:Smoking, complement component, total protein, amylase, EBV
Objective: The present study aimed to shed light on the role of narghileh and cigarette smoking on immunity
status of oral cavity by assess (C3 complement component, Immunoglobulin A, Total protein, ?-Amylase
and EBV IgG antibody).
Method: Saliva levels in two smokers groups the first include 28 narghileh smokers and the second include
32 narghileh and cigarette smokers as well as 30 non-smokers consider as control.
Results: As compared control, the levels of C3, IgA and total protein were significantly decreased, and the
highest decreased was observed in saliva of narghileh and cigarette smokers, the result was (C3= 0.400 ±
0.194µg vs. 9.728 ± 3.561µg; IgA= 2.460 ± 0.492mg/dl vs. 5.048 ± 0.937mg/dl; Total protein= 170.20 ±
45.93mg% vs. 452.20 ± 136.57mg%, respectively) while the level of ?-amylase was slightly dropped but
with a non-significant, the result was (246.37 ± 122.47,243.56 ± 178.69 vs,213.51 ± 101.88) respectively.
Conclusion: The narghileh and cigarette can alter the microenvironment of oral cavity and influence the
immunity of mucosa tissue, then increase the risky for many diseases such as blood hypertension, heart
diseases, and lung diseases and may contribute to a variety of cancer.
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