Anti-Islet Cell Antibody and Anti-ovarian Antibody Levels in Iraqi Women with Polycystic Ovary Syndrome

Authors

  • Zainab Ali Hlail1 , Ahmed Sahib Abd-ulamir2 , Khalil Ismail Abd-Mohammed3, Mohammed Odah Salman3

DOI:

https://doi.org/10.37506/mlu.v21i1.2463

Keywords:

Anti-Islet, Antibody, Anti-ovarian, Iraqi women

Abstract

Objective: The objective of this analysis was to assess serum islet cell anti-bodies concentrations and antiovarian anti-bodies in the relationship between the PCOS patient and the stable control group.
Material and Method: In this study, 250 Iraqi women aged between 20-50 years were studied. The patients
were divided into two groups: study group (n=125, PCOS women) and age-matched controls group (n=125
normal women). The blood sample was obtained on the 2nd day of menstruation cycle. Islet cells Ab and
anti ovarian Ab concentrations were determined in both groups.
Results: Women with PCOS had higher serum islet cell concentrations higher than control levels (p < 0.05).
The levels of islet cells Ab and Anti-ovarian Ab were substantially positively associated with BMI, high
levels of anti-mullerian hormone (AMH) and insulin resistance.
Conclusion: The evidence from this study indicated that serum Islet cells Ab and anti-ovarian Ab levels in
women with PCOS were observed to be higher compared with controls. Elevated serum Islet cells Ab and
anti-ovarian Ab levels can be associated with high AMH and insulin resistance.
Keywords: Islet cells, anti-ovarian Ab, anti-mullerian hormone, body mass index, polycystic ovary
syndrome.

Author Biography

Zainab Ali Hlail1 , Ahmed Sahib Abd-ulamir2 , Khalil Ismail Abd-Mohammed3, Mohammed Odah Salman3

1Lecturer, College of Medicine/University of Baghdad, Baghdad, Iraq, 2Prof., College of Medicine/Al-Nahrain
University, Baghdad, Iraq, 3
Prof. High Institute of Infertility Diagnosis and Assisted Reproductive Technology
(ART)/Al-Nahrain University, Baghdad, Iraq

Published

2021-01-09

How to Cite

Zainab Ali Hlail1 , Ahmed Sahib Abd-ulamir2 , Khalil Ismail Abd-Mohammed3, Mohammed Odah Salman3. (2021). Anti-Islet Cell Antibody and Anti-ovarian Antibody Levels in Iraqi Women with Polycystic Ovary Syndrome. Medico Legal Update, 21(1), 1098-1101. https://doi.org/10.37506/mlu.v21i1.2463

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