Relations between Interlukin-6 and Some Biochemical Parameters in Diabetic Foot Syndrome
Keywords:Diabetic foot syndrome, Diabetes mellitus type 2, Diabetic neuropathy, FBG, IL-6, and oxidative stress.
The aim of this study is to predict the incidence of diabetic foot syndrome in type 2 diabetic patients by
measuring some parameters (IL-6, FBS, MDA, CP, BMI). Samples were obtained from (75) type II diabetic
patients with and without diabetic complications (diabetic foot and diabetic neuropathy), as well as (25)
healthy controls as a control group. They were divided into four groups: Group A (the control group):-
It included (25) healthy individuals aged between (35-70 years). Group B (Diabetics type II without
complications):- Includes (25) patients, their ages range (35-70 years). Group C (diabetic patients with
diabetic neuropathy):- It included (25) patients whose ages ranged from (35-70 years). Group D (diabetic
patients with diabetic foot syndrome): - Included (25) patients whose ages ranged from (35-70 years). The
results showed a significant increase in the levels of (IL-6, FBS, MDA, CP) in all groups of type II diabetes
patients with and without complications compared to the control group (P? 0.05). There was a significant
increase in the parameters measured in the group of diabetic patients with type II diabetic foot syndrome
(DF) compared to the group of diabetic patients with type II disease Diabetic neuropathy (DN), and the
results also showed a significant increase in group DN compared to group of type II diabetic patients (DM)
(P? 0.05). Our study show Interleukin-6 values, as well as oxidative stress, could predict the future incidence
of diabetic foot syndrome.
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