Effect of Polycythemia on Serum Lipid Profile and Oxidative Stress

Authors

  • Zainab Qasim1 , Muhammad Al-Yasiri1

DOI:

https://doi.org/10.37506/mlu.v21i1.2556

Keywords:

Polycythemia, lipid profile, oxidative stress.

Abstract

Polycythemia is generally known as a disorder that affects the stem cells in the bone marrow and is characterized
by a high and excessive production of red blood cells. The current study was designed to investigate and
investigate the relationship between the serum lipid profile and oxidative stress in polycythemia patients.,
The study included examining 85 blood samples from both gender, males and females, for patients coming
to Shatra General Hospital. During the study period, all of (Hb, PCV, MDA, TC, TG, HDL, LDL, and
VLDL) were examined for both patients and control groups.
The current study showed an increase in the incidence of polycythemia in males, while it decreased in
females, and the study showed that the incidence of polycythemia increased with age until it reached its
peak in the third age group 41-50 years, then the percentage gradually decreased to a minimum in the fifth
age group 61-70 years .
The results of the study recorded a significant increase P <o.o5 in both the concentration of hemoglobin Hb
and the packed cell volume PCV in patients with polycythemia, both real and secondary, when compared
with the control group. Also, the results of the present study showed: a significant decrease P <0.05 in
cholesterol concentration in the group of true polycythemia compared with the control group. A significant
increase P <0.05 in concentration of triglycerides (TG) was higher in the true polycythemia group and a high
significant P <0.05 in the secondary polycythemia group compared with the control group.
The results indicated that there was a significant decrease P <0.05 in LDL concentration in the true
polycythemia group, and a significant increase of P <0.o5 in the secondary polycythemia group compared
with the control group. The results of the study also recorded a high significant decrease P <0.05 in the true
polycythemia group and a significant decrease P <0.o5 in the secondary polycythemia group compared to
the control group. The results also showed a significant increase P <0.05 with the concentration of VLDL in
the group of true polycythemia and high Significant p <0.05 in the secondary polycythemia group compared
with the control group.
The results showed a significant increase P <0.05 in MDA concentration in polycythemia patients compared
with the control group.

Author Biography

Zainab Qasim1 , Muhammad Al-Yasiri1

1Assistant Lect., Biology Department, College of Education for Girls, DhiQar University, Iraq

Published

2021-01-09

How to Cite

Zainab Qasim1 , Muhammad Al-Yasiri1. (2021). Effect of Polycythemia on Serum Lipid Profile and Oxidative Stress. Medico Legal Update, 21(1), 1640-1649. https://doi.org/10.37506/mlu.v21i1.2556