Study of Some Immunological Markers of People with Parasitic Infestation and their Relationship to Colorectal Cancer

Authors

  • Ali Slwmee. Serhan Al-halaly
  • Habeeb Waseel Kadhum Shubber

DOI:

https://doi.org/10.37506/mlu.v21i2.2651

Keywords:

Colorectal cancer, mucin 2, TFF3, CALP

Abstract

The aims of this study to find the link between each of the parasites(E. histolytic and Giardiasis) infection
and intestinal cancer, This study contain 4 groups :- Group (G1) People with cancer and diarrhea due to
the parasite (42) Group (G2) People with cancer and diarrhea without parasites (8) Group (G3) People
with diarrhea and parasites (24) and Group (G4) Control (30), blood samples were collected from patients
suffering from diarrhea and parasite infection of both types, as well as cancer, Elisa kits were used in our
study the proteins (mucin 2, TFF3, CALP) level were measure by using Elisa kit that provided from the
China Origin Company Elabscience. The results of the current immunological study showed the level of
serum (mucin 2, TFF3, CALP) among the study groups, where the levels of mucin 2 values were (14305.00),
(10595.00),(13145.00) and (9350.00)in group (1), and group (2), group (3) and group (4) respectively,
and the level of serum values (TFF3)(43.15),(11.90),(29.65) and (8.60)with the same sequence of groups
above, and the level of serum values CALP(16320.00),(11220.00),(15275.00) and(8690.00)with the same
sequence of groups above as well. The results of the statistical analysis showed that there is a significant
difference between the study groups below the probability level (P<0.001). (mucin 2, TFF3, CALP) with
both (carcinogenic parasite) and (parasitic infestation only) and (carcinogenic infection) with different high
levels compared to other groups.
Our study was concluded there was relationship between E. histolytic and Giardia lamblia infection and
intestinal cancer .

Author Biographies

Ali Slwmee. Serhan Al-halaly

Research

Habeeb Waseel Kadhum Shubber

Assit. Prof., University of Al-Qadisiyah/College of Science/Department of Biology, Iraq

Published

2021-03-12

How to Cite

Ali Slwmee. Serhan Al-halaly, & Habeeb Waseel Kadhum Shubber. (2021). Study of Some Immunological Markers of People with Parasitic Infestation and their Relationship to Colorectal Cancer. Medico Legal Update, 21(2), 82-88. https://doi.org/10.37506/mlu.v21i2.2651

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