Targeting Gut Microbiome and the Recovery of Muscle Loss Associated with Cancer (Cachexia): An Overview of the Possible Effect of Bee Products

Authors

  • Amira Mohammed Ali
  • Esraa Mohammed Ali
  • Mostafa Elsayed Ahmed
  • Amin Omar Hendawy

DOI:

https://doi.org/10.37506/mlu.v21i2.2665

Keywords:

Bee honey, cachexia,cancer,gut microbiome/microbiota, gut-muscle axis, probiotics, propolis, skeletal muscle loss.

Abstract

Current research emphasizes the contribution of gut microbiome to numerous health conditions including
cancer and skeletomuscular disorders. Cachexia is a debilitating condition of progressive loss of body
tissues. It occurs in up to 80% of patients with tumors, and it impairs their functioning and quality of life and
increases morbidity and premature death. Several randomized trials indicate that interventions, which target
gut microbiome can correct and revert tissue loss in aged people. However, less is known about the effect
of such strategies in cachectic muscle loss. This report briefly sheds the light on the role of gut-muscle axis
in cachexia and demonstrates few examples on interventions addressing gut microbiome and their effect on
cachectic muscle. It also speculates the literature for the skeletal muscle-promoting activity of bee products,
particularly bee honey and propolis (which are quite handy), within the context of cachexia. Implications for
future studies are discussed.

Author Biographies

Amira Mohammed Ali

Postdoctoral Fellow, Department of Mental Disorder Research, National Institute of Neuroscience, National
Center of Neurology and Psychiatry, Tokyo, Japan

Esraa Mohammed Ali

Lecturer, Department of Educational
Sciences, Faculty of Early Childhood Education, Alexandria University, Alexandria, Egypt

Mostafa Elsayed Ahmed

Assistant Lecturer,
Department of Plant Protection, Faculty of Agriculture, Damanhour University, Damanhour, Egypt

Amin Omar Hendawy

Lecturer,
Department of Animal and Poultry Production, Faculty of Agriculture, Damanhour University, Damanhour, Egypt

Published

2021-03-12

How to Cite

Amira Mohammed Ali, Esraa Mohammed Ali, Mostafa Elsayed Ahmed, & Amin Omar Hendawy. (2021). Targeting Gut Microbiome and the Recovery of Muscle Loss Associated with Cancer (Cachexia): An Overview of the Possible Effect of Bee Products. Medico Legal Update, 21(2), 163-171. https://doi.org/10.37506/mlu.v21i2.2665