Common Hemoglobinopathies for Couples Premarital Individual and its Influence on Hemostasis and Immune State
Keywords:Hemoglobinopathies, Premarital Individual, hemostasis, immune state.
Before marriage, couples are screened through a procedure known as premarital screening for different
genetic, infectious or bloodborne diseases that can be passed from them to their offspring. The aim of our
research was to assessment the premarital screening of couples for hemoglobinopathies and undiagnosed
cases with suggestive findings of thalassemia or its variants. and evaluation hematology parameters among
common Hb hemoglobinopathy. This study contains 228 individuals with hemoglobinopathy, the participants
were couples attending primary health centers for regular premarital inquiries in baquba teaching hospitals,
Iraq. ?-thalassemia was enrolled in 3 (1.3%) from all hemoglobinopathy individuals, ?-thalassemia was
enrolled in 255 (98.8 %), which include ?-thalassemia minor in 226 individuals 88.6%, while ? thalassemia
intermediate in 5 individuals 2.2% from all individuals with hemoglobinopathy Figure 1 and 2. Others
thalassemia was recorded 3 Hb-E 1.1%, 1 Hb-S 0.39, 10 Hb-D 3.92, 13Hb-C 5.09. Pre-marital examinations
are important to determine hemoglobinopathy and limit transmission to offspring, as well as blood tests are
important to identify people with haemoglobinopathy and its influence.
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