Rate of Hypokalemia and Risk Factors in Patients on Peritoneal Dialysis Under PD First Policy

Authors

  • Sajja Tatiyanupanwong
  • Wongsa Laohasiriwong
  • Nathaphob Chaichaya
  • Bandit Thinkhamrop
  • Pokkrong Limpwanta
  • Jadsada Thinkhamrop
  • Siribha Changsirikulchai

DOI:

https://doi.org/10.37506/mlu.v21i2.2827

Keywords:

Electrolyte, potassium, hypokalemia, dialysis, peritoneal dialysis, CAPD PD First, Thailand

Abstract

Background: Hypokalemia is common among peritoneal dialysis (PD) patients. The incidence rate of
hypokalemia and risk factors were investigated.
Material and Method: A retrospective cohort, enrolled 1,044 incident PD patients under the Universal Health
Coverage(UHC) Scheme of a regional hospital between January 2012 and December 2018. Hypokalemia
was defined as having serum potassium less than 3.5mEq/L. The rate of hypokalemia in episodes per one
year at risk was determined. Risk factors of hypokalemia were reported as an incidence rate ratio using
Poisson regression.
Results: The incidence rate of hypokalemia was 2.21(95% confidence interval, 2.14-2.27)episodes per one
year at risk. Risk factors of hypokalemia were ; older than 60 years, female, diabetes, bodyweight less than
45 kg, serum albumin less than 3.5 g/dL, serum phosphate less than 2.5 mg/dL, and total lymphocyte count
less than 1,500 cells/mm3
.
Conclusions: Hypokalemia was frequently occurred in PD patients. Elderly PD patients, female, diabetes,
malnutrition, low serum albumin, and lowserum phosphate had higher risks to develop hypokalemia.

Author Biographies

Sajja Tatiyanupanwong

Doctor of Philosophy in Epidemiology and Biostatistics (International Program), Chaiyaphum Hospital,
Chaiyaphum, Thailand

Wongsa Laohasiriwong

Associate Professor, Faculty of Public Health, KhonKaen University, Thailand

Nathaphob Chaichaya

Statistician, Data Management and Statistical Analysis Center (DAMASAC), Faculty of Public Health, KhonKaen
University, Thailand

Bandit Thinkhamrop

Statistician, Data Management and Statistical Analysis Center (DAMASAC), Faculty of Public Health, KhonKaen
University, Thailand

Pokkrong Limpwanta

Doctor of Philosophy in Epidemiology and Biostatistics (International Program), Chaiyaphum Hospital,
Chaiyaphum, Thailand

Jadsada Thinkhamrop

Professor, Department of Obstetrics and Gynecology, Faculty of Medicine, KhonKaen
University, Thailand

Siribha Changsirikulchai

Associate Professor, Division of Nephrology, Department of Medicine, Faculty of Medicine,
Srinakharinwirot University, Thailand

Published

2021-03-12

How to Cite

Sajja Tatiyanupanwong, Wongsa Laohasiriwong, Nathaphob Chaichaya, Bandit Thinkhamrop, Pokkrong Limpwanta, Jadsada Thinkhamrop, & Siribha Changsirikulchai. (2021). Rate of Hypokalemia and Risk Factors in Patients on Peritoneal Dialysis Under PD First Policy. Medico Legal Update, 21(2), 1067-1073. https://doi.org/10.37506/mlu.v21i2.2827