Association of Bleeding Time and Clotting Time with ABO Blood Groups Among Healthy Adults

Authors

  • Mangala Gowri S.R., Dr. Kancharla Sirisha Associate Professor

DOI:

https://doi.org/10.37506/ijop.v7i4.106

Keywords:

ABO Blood groups, Bleeding Time, Clotting Time.

Abstract

Background

Haemostasis is the stoppage of bleeding. Bleeding time (BT) and Clotting time (CT) assess the integrity of haemostatic mechanisms. Assessment of Hematological parameters like bleeding time, clotting time and blood grouping are a very important before initiating any surgical procedure. Blood group has clinical importance in transfusion medicine and medico legal cases. Some studies have showed epistaxis and thrombosis found in O blood group individuals. Earlier studies showed the conflicting results regarding association of blood group with clotting time and bleeding time.

Objectives

The aim of the study was to assess the distribution of ABO blood groups in males and females with age group of 17-21yrs and determination of BT and CT among males & females. To analyze the relationship between the blood groups, BT and CT.

Method

The study was conducted in Department of Physiology, Mamata Medical College. The study included 205 healthy volunteers of age group between 18-21years. Blood grouping, bleeding time and clotting time were determined. Statistical analysis done by un paired t test for calculating gender wise CT and BT and ANOVA and Post Hoc test for assessing relationship between BT, CT and blood groups.

Results

Our study results showed that blood group O was predominant in both males and females. Clotting time and bleeding time is statistically higher in females compared to males. Results showed clotting time is statistically significant (0.011) only between group A & group O, with higher value in group O but not the bleeding time.

Conclusion

Blood group O was the most common group. BT and CT were higher in females than males. May be due to high estrogen and lower fibrinogen levels in females. CT and BT maximum in blood group O due to more activation of von Willebrand's Factor.

Author Biography

Mangala Gowri S.R., Dr. Kancharla Sirisha , Associate Professor

Gowri S.R. Mangala1, Dr. Sirisha Kancharla2,*

1Associate Professor, Department of Physiology, Mamata Medical College, Khammam, Telangana

2Assistant Professor, Department of Physiology, Mamata Medical College, Khammam, Telangana

Published

2019-11-21

How to Cite

Mangala Gowri S.R., Dr. Kancharla Sirisha. (2019). Association of Bleeding Time and Clotting Time with ABO Blood Groups Among Healthy Adults. International Journal of Physiology, 7(4), 114–119. https://doi.org/10.37506/ijop.v7i4.106