Effect of Caffeine on Multi-domain Neurocognitive Abilities in Occasional Coffee Consumers
Keywords:Caffeine, Auditory Reaction Time, Visual Reaction Time, Critical Flicker Fusion Frequency, Digits forward test.
Background: Multi-domain neurocognitive abilities underpin timely perception & appropriate action to
unexpected threats in the dynamic environment. Hence enhancement of the same may be life-saving in some
situations. Caffeine is the most widely consumed CNS stimulant which not only enhances neurocognitive
abilities but also temporarily counteracts neurocognitive deficits. Therefore this study has been undertaken
to quantify the effect of Caffeine on Multi-domain neurocognitive skills.
Aim: To find out the effect of Caffeine on neurocognitive abilities in occasional coffee consumers
Materials & Methods: This study was conducted on 23 participants. In all the subjects under basal
conditions, a battery of multi-domain neurocognitive tests, which included ART, VRT, CFFF, Digits forward
tests were conducted. Then a standard dose of 2.2grams of instant coffee powder (Nestle – 69.6mg of
Caffeine) dissolved in 100 ml of milk was given. After 30 minutes of intake, the same battery of tests was
repeated, and the test results were analyzed.
Results: In our study, we have found that Caffeine significantly increases CFFF (p<0.001), Digits forward
test score (p<0.001) and decreases VRT (p=0.03). It also reduces ART, but it is not statistically significant.
Conclusion: Caffeine significantly improves Critical flicker fusion frequency, attention span, performance
and reduces reaction time.
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