Study of Cardiovascular Parameters and Heart Rate Variability (Frequency Domain Analysis) in 1St Trimester of Normal Pregnant Women and Pregnant Women with Risk Factors for PIH in Western Rajasthan

Authors

  • Soniya Vyas
  • Raghuveer Choudhary
  • Kamla Choudhary
  • Islam Khan

DOI:

https://doi.org/10.37506/ijop.v9i4.3170

Keywords:

PIH, Heart Rate Variability, pregnancy, autonomic nervous system

Abstract

Background: The role of sympathovagal imbalance (SVI) and CV risk in pregnancy-induced
hypertension (PIH) has been reported, and their association during early trimesters of gestation in PIH
has not been studied. Therefore, in the present study, we have investigated the maternal cardiovascular
parameters and frequency domain indices of Heart rate variability (HRV) between normal pregnant
women and women with risk factors for PIH in their 1st trimester of gestation.
Methods: Two hundred twenty subjects each (220 of normotensive pregnant women i.e., control group
and 220 of pregnant women with risk factor for PIH i.e., study group) of 1st trimester of gestation were
recruited from the obstetrics & gynecology department of Umaid hospital, associated with Dr. S. N.
Medical College, Jodhpur, Rajasthan. Physical examination was done and anthropometric measurement
like height & weight were taken. The collected data was statistically analyzed using HRV analysis
software.
Results: Significant difference in body mass index was observed between the two groups. Systolic blood
pressure, Diastolic blood pressure, Pulse pressure, Rate pressure product and Mean arterial pressure of
study group was significantly higher than control group. Values of LF and LF/HF ratio components of
frequency domain analysis of HRV were significantly increased but HF component is non significantly
decrease in 1st trimester of the pregnant women with risk factor for PIH than normal pregnant women.
Conclusion: The present study indicates that the cardiovascular parameters in 1st trimester of pregnant
women with risk factor for PIH were increased highly significantly than the normal pregnant women.
The highly significant (HS) (p<0.000) increase in the LF (nu) & LF/HF ratio and non significant (NS)
(p<0.552) decrease in HF (nu) of pregnant women with risk factors for PIH was observed than normal
pregnant women this indicate that sympathetic tone was increased in 1st trimester of pregnant women
with risk factor for PIH. Vagal withdrawal and sympathetic exaggeration may be the possible cause of
PIH in pregnant women with its risk factors.

Author Biographies

Soniya Vyas

PhD Scholar, Department of Physiology, Dr. S. N. Medical College, Jodhpur, Rajasthan

Raghuveer Choudhary

Senior Professor & Head of Physiology Department, Dr. S. N. Medical College, Jodhpur, Rajasthan

Kamla Choudhary

Associate Professor, Department of Physiology, Dr. S. N. Medical College, Jodhpur, Rajasthan

Islam Khan

Senior Demonstrator. Department of Physiology, Dr. S. N. Medical College, Jodhpur, Rajasthan

Published

2021-08-27

How to Cite

Soniya Vyas, Raghuveer Choudhary, Kamla Choudhary, & Islam Khan. (2021). Study of Cardiovascular Parameters and Heart Rate Variability (Frequency Domain Analysis) in 1St Trimester of Normal Pregnant Women and Pregnant Women with Risk Factors for PIH in Western Rajasthan. International Journal of Physiology, 9(4), 39-45. https://doi.org/10.37506/ijop.v9i4.3170