Study of Pattern of Dyslipidaemia among Type 2 Diabetes Mellitus Patients Seeking Care in GMERS Medical College Patan, Gujarat, India
Keywords:Glycaemic control, HbA1c, Dyslipidemia, Cardiovascular risk.
Patients with type-2 diabetes have increased risk of myocardial infarction associated with atherogenic dyslipidemia. The diabetic dyslipidemia is characterised by elevations of low density lipoproteins (LDL), triglycerides (TG) and decreased high density lipoproteins (HDL). Lipid particles in diabetic dyslipidemia patients are more atherogenic than in non-diabetic people. Therefore, lipid abnormalities in diabetes should be aggressively treated the at the earlier.
(a) To study the pattern of dyslipidemia in diabetic patients, and (b) To compare lipid profile among patients with poor glycaemic control and good glycaemic control patients. (c) To access cardiovascular risk status according to criteria of Adult treatment panel III of National Cholesterol Education Program (NCEP).
Material & Method
The present study was carried out at GMERS medical college, Patan Gujarat during period from July 2018 to December 2018. All patient was advised for 12–14 hours overnight fasting and blood samples were collected on next morning before breakfast for lipid profile, FBS, PPBS, HbA1C. Cardiovascular risk status was evaluated according to the criteria of Adult treatment panel III of National Cholesterol Education Program (NCEP).
Out of 150 patients, 46 (30.6%) patients had good glycaemic control and 104 (69.4%) had poor glycaemic control. The patients with poor glycaemic control are at borderline to high cardiovascular risk status as determined by TG and LDL-C levels and serum cholesterol levels.
From the present study we can conclude that diabetic patients with poor glycaemic control are at higher cardiovascular risk according to serum cholesterol, LDL-C levels and TG levels. In addition to glycemic control, HbA1c can be utilized as a potential biomarker to predict dyslipidemia in type 2 diabetic patients
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