Electrodiagnostic Features of Ulnar Nerve in Patients with Chronic Obstructive Pulmonary Disease
DOI:
https://doi.org/10.37506/ijop.v7i4.88Keywords:
Nerve conduction study, hypoxemia, demyelination, axonal loss.Abstract
Background & Objectives
Present study was aimed to assess abnormalities of ulnar nerve in stable COPD patients.
Method
Study comprised of 60 healthy adults and 60 stable COPD patients (40–50 years) with no clinical neuropathy. Duration of illness and spirometric indices (FEV1%, FEV1/FVC, PEFR %) were assessed. Nerve conduction study of motor and sensory component of ulnar nerve was recorded bilaterally using RMS EMG MKII. Distal latency, nerve conduction velocity and compound motor action potential (CMAP) and sensory nerve action potential (SNAP) were analysed. Significant abnormality was defined as variations beyond mean ± 2SD from healthy adults.
Results
Observations revealed significantly prolonged distal latency and decreased conduction velocity (demyelination), decreased CMAP (axonal loss) bilaterally of both sensory and motor components of ulnar nerve in COPD patients compared with controls.
Interpretation & conclusion
Observation suggests that hypoxemia of COPD, by inducing direct action on nerve fibres or pontomedullary portion of brain or by enhancing effect of other neurotoxic substances causes nerve impairmen
Downloads
Published
Issue
Section
License
Copyright Ownership: Authors retain copyright ownership of their work after publication in IJOP. However, they grant the journal an exclusive Creative Commons license.
Creative Commons License: The authors grant IJOP the right to exclusively apply a Creative Commons license to their work upon publication. This license permits use, distribution, and reproduction of the work in any medium, provided that the original work and its source are properly cited. The specific license applied is Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0), which allows for attribution, non-commercial use, and derivative works.
Editorial Research: Authors grant the journal the right to analyze information obtained from submitted manuscripts for editorial research purposes. This analysis aims to improve the peer-review process, teaching, and training activities.
Warranties: Authors warrant that their work is original, contains no libelous statements, is lawful, and does not infringe upon any copyright, trademark, patent, or proprietary rights of others. Authors agree to indemnify the editors against any costs, expenses, and damages arising from any breach of this warranty.
Views and Opinions: The views and opinions expressed in the article are those of the authors and not necessarily those of the journal.