Acute Effect of Hemodialysis on Cognition in Patient of End Stage Renal Disease

Authors

  • Sanaul Mustafa Ansari, Kumar Siddharth, Ashok Sharan Junior Resident

DOI:

https://doi.org/10.37506/ijop.v7i4.91

Keywords:

Hemodialysis, cognitive control, Stroop Color Word Test.

Abstract

Aim

To assess effect of hemodialysis on cognitive control.

Introduction

Studies till date have not confirmed the immediate effect of hemodialysis on cognitive function. Cognitive control consists of core cognitive functions such as working memory and inhibition. In several studies it was observed that patients performed worse than healthy control in terms of fluency, working memory, inhibitory control, cognitive flexibility, and decision-making. This study was specifically designed to observe the effect of hemodialysis on learning and memory (Cognitive Control) in fifty ambulatory male subjects of end stage renal disease undergoing twice a week hemodialysis of age more than 21years.

Material and Method

Subjects on hemodialysis for more than 2 months up to a year were only included. They were instructed about methodology of Stroop color Word Test, Backward digit span Test and Ray Auditory Verbal learning Test. Following instruction on methodology they were given five practice sessions. They were then tested before and after hemodialysis.

Result

Post hemodialysis, the reaction time for Stroop color condition, Stroop word condition and Strop color word condition was less and this was found to be statistically significant when compared to pre hemodialysis. This indicates an improvement in executive control acutely after dialysis. If we look at backward digit span test and RAVLT total score, delayed recall and average recall no significant change was seen. The RAVLT immediate recall time changed significantly after hemodialysis.

Conclusion

There is acute effect of hemodialysis on executive function (cognitive control) domain of cognition.

Author Biography

Sanaul Mustafa Ansari, Kumar Siddharth, Ashok Sharan , Junior Resident

Ansari Sanaul Mustafa1, Siddharth Kumar1,*, Sharan Ashok2

1Junior Resident (Academic), Department of Physiology, Indira Gandhi Institute of Medical Sciences, Patna

2Professor& Head, Department of Physiology, Indira Gandhi Institute of Medical Sciences, Patna

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Published

2019-11-21

How to Cite

Sanaul Mustafa Ansari, Kumar Siddharth, Ashok Sharan. (2019). Acute Effect of Hemodialysis on Cognition in Patient of End Stage Renal Disease. International Journal of Physiology, 7(4), 203–207. https://doi.org/10.37506/ijop.v7i4.91