Histological Investigations for Cordia Myxa During the Treatment of Gastritis in Local Rabbits

Abstract

Background: The goal of this study was to evaluate the effect of medical fruits, through H+ proton pump

inhibitors and observation to main of histological changes accompanying for treatment. Methods, Adult

domestic healthy rabbits, all experimental animals were adapted in animal house. Animals were taken for

this study distributed into three group, control (5 ml/kg b.w) gastritis (10% glacial acetic acid 1ml//kg b.w)

and treatment group (5 ml/kg b.w) oral administration during 21 day for 3 time daily.

Results: the main histological observations for effects of (Juicer fruit Bumper) during induce inflammation

by 10% acetic acid, after 4hr showing the inflammation region in internal surface in fundic region but most

of internal surface it’s normally. Histologically, the stomach of gastritis group was observed the erosion in

epithelia surface and congestion of blood vessels, gastric pits disappear but most of changes which accrue in

lamina propria generally. The rabbits of treated group was observed reductions in inflammatory area, with

some extent of mucosal regeneration (re-epithelization) and the parietal cells appeared a granular cytoplasm

and proliferation of connective tissue cells (granulation tissue).

Conclusions: these findings suggest that (Cordia myxa) considered perfect anti-inflammatory and H+ proton

inhibited pump