Serum ?–Amylase Level in Sudanese Patients with Long Standing Diabetes Mellitus Type 2 in Khartoum State, Central Sudan

Authors

  • Akram H. Awadalla1, Ahmed M. Ahmed2, Saifeldein Babiker Abdalla3, Ahmad M. Saleh4, Ahmad Khaleel AlOmari5

DOI:

https://doi.org/10.37506/mlu.v20i4.1757

Keywords:

α-amylase, Diabetes Mellitus, Pancreas exocrine Insufficiency

Abstract

Objectives: To evaluate and correlate the serum activity of ?-amylase in Sudanese patients with type 2 long
standing diabetes mellitus.
Methodology: This is a descriptive, cross- sectional, hospital based, case- control study was done in fifty
patients (twenty male &thirty female) above forty yearswith long period diabetes mellitus type 2 referred
to Jabber Abu ElizDiabetes Center and Bahri Diabetes Center in Khartoum state in central Sudan within
six months. Thirty healthy volunteers with matching age and sex and socioeconomic status were included.
Data was collected through, clinical evaluation form, questionnaire, and laboratory investigations. Serum
concentrations of ?- amylasewere measured by spectrophotometer and t test and correlation were used in
statistical analysis for the comparison between test and control group for example: control group.
Results: The result showed a significant difference between the mean of serum ?- amylase of the control
group compared with that of the test group (Mean ±SD): (39.83±9.0) versus (32.22±13.5) U/L respectively,
(P<0.05). Also, there wasa significant positive correlation between the levels of ?- amylase and the duration
of diabetes mellitus. Correlation coefficient (r) = (r = 0.27, P= 0.000) for example: 0.0000.
Conclusion: From this study it was concluded that; the diminution of the serum levels of ?- amylase could
be part of the exocrine pancreatic insufficiency since ?- amylase activity decline correlated well with the
duration of long-standing type 2 Diabetes Mellitus.

Author Biography

  • Akram H. Awadalla1, Ahmed M. Ahmed2, Saifeldein Babiker Abdalla3, Ahmad M. Saleh4, Ahmad Khaleel AlOmari5

    1Associate Professor, Division of Clinical Chemistry, Faculty of Medical Laboratory Sciences, University of
    Kordofan, Elobied, Sudan, 2Associate Professor, Department of Clinical Laboratory Sciences, Faculty of Applied
    Medical Sciences, Taibah University, Medina, Saudi Arabia, 3Assistant Professor, Division of Clinical Chemistry,
    Faculty of Medical Laboratories, College of Applied Medical Sciences, Jazan University, Saudi Arabia, 4Assistant
    Professor, Department of Nursing, College of Applied Medical Sciences, Prince Sattam Bin Abdulaziz University,
    Alkharj, Riyadh, Saudi Arabia, 5Assistant Professor, Department of Biomedical Technology, College of Applied
    Medical Sciences, Prince Sattam Bin Abdulaziz University, Alkharj, Riyadh, Saudi Arabia

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Published

2020-11-18

Issue

Vol. 20 No. 4 (2020): Medico-Legal Update

Section

Articles

How to Cite

Serum ?–Amylase Level in Sudanese Patients with Long Standing Diabetes Mellitus Type 2 in Khartoum State, Central Sudan. (2020). Medico Legal Update, 20(4), 31-34. https://doi.org/10.37506/mlu.v20i4.1757