Risk of Incident Rheumatoid Arthritis Related to Anemia and Associated with CRP

Abstract

Background and Objective: Rheumatoid arthritis (RA) is a chronic systemic inflammatory an autoimmune
disease characterized by the articular and extra-articular manifestation as weight loss, fatigue, malaise, and
anemia. This study aimed to find the prevalence of metabolic syndrome in its correlation with the disease
activity among patients with RA in Al-Najaf province and to determine the associated risk factors this
study including 75 Subjects was 50 suffering from rheumatoid arthritis and 25 subjects were healthy. Full
blood count, erythrocyte sedimentation rate platelet count was determined using standard hematologic
method. The result in this study exhibits there is significant decrease in (hematological characteristic) RBC
number, while increase in WBC number spatially neutrophil, platelet, glucose and ESR in patients with
arthritis in comparison with control. This result indicated that no significant difference (P>0.05) in the mean
hematological characteristic RBC number, WBC number spatially neutrophil, platelet when compared with
between Positive and negative C –reactive protein in patient with arthritis. The results revealed a significant
increase (P<0.05) in mean of ESR of patients with positive C –reactive protein in compared with negative
C –reactive protein in patient with arthritis.
Conclusions: Rheumatoid arthritis patients have a variety of abnormalities in hematologic characterize. RA
disease can be linked with anemia of chronic inflammation, leukocytosis, and thrombocytosis. Also, in our
study, we concluded that little evidence found between disease activity and anemia. ESR and C-reactive
protein related to the activity of RA disease.