Effect of Blood Groups and Complications on Orofacial Measurements of B Thalassemia Adult Patients

Abstract

Background: ?- thalassaemia is a common hereditary disorders in Iraq and worldwide .with different
treatment schemes,, including blood transfusion, iron chelation and splenectomy, patients with B thalassemia
may develop different skeletal changes. Limited studies link these complications with orofacial changes,
This study aimed to evaluate the orofacial dimensions in ?- thalassemia patients with age, gender, blood
groups, splenectomy and cholecystectomy and to assist surgeons for planning their future intervention.
Method: This study was conducted on 130 ß-thalassemia patients of both gender,,and two age categories (20-
30 yrs), & (21-40 yrs), five orofacial measurements (face,eyes,nose,mouth and ears) and sixteen parameters
were measured and calculated for differences,P value is estimated,data analysis were done by using Chi
square test and SPSS version 20
Results: Significant findings were found for mandibular width and mouth width at older age group (31-40
years), the nasal width and ear height are more in male, patients with splenectomy have significance for
lower 1\3 face and ear width. Cholecystectomy increase eye length measurments and ear height but for
blood groups the P ? 0.05
Conclusions: Orofacial bone changes are pronounced in ?- thalassaemia with distinct findings regarding sex
dimorphism, older are more prone to have variations, earlier splenectomy is advisable,cholecystectomy is
better choice for symptomatic patients, blood groups have no significance.