Evaluation Follicular Fluid Cytokines in Patients with Risk Factor for Development of Ovarian Hyper Stimulation Syndrome

Abstract

Aim of Study: Study the level of IL17 and IL23 in the follicular fluid and their relation with hyper stimulation
syndrome.
Materials/Method: Eighty five who include (85 subject divided into 2 groups, control group whom included
infertile female with male factor infertility (55) and case group whom infertility due to poly cystic ovarian
syndrome (30) attended IVF centre.
Samples collected were follicular fluid, the follicular fluid has been collected in Eppendorf tube then stored
at -20c to be used for ELISA test to determine concentration of IL 23 and IL 17 in follicular fluid. The results
were analyzed using the IBM SPSS analytic software.
Results: the mean of interleukin (IL17) 96.11, Standard deviation 78.46 in the patients group. While the
mean of interleukin (IL 17) for control 6.15, Standard deviation 14.33. There was a significant difference
between polycystic and male factor infertility. P value < 0.005 both of them groups Poly cystic and male
factor.
Conclusions: High concentration of follicular fluid IL -17 is positively associated with e disease of poly
cystic ovary (POCS).