Rare Case of Mediastinal Synovial Sarcoma in an Indonesian Woman
Keywords:Synovial sarcoma mediastinum, malignant tumor, poor prognosis.
Background: Synovial sarcoma mediastinum is a rare tumor, with a few cases having been reported.
Case Presentation: A 27-year-old Indonesian woman had a complaint of shortness of breath and left chest
pain. Chest X-ray showed a massive pleural effusion with reddish-yellow pleural fluid. Thorax CT scan
showed a clear demarcated mass in the anterior mediastinum until left medius, with value of lactic acid
dehydrogenase of 561 U/L. The patient was diagnosed with mediastinal tumor and performed left anterolateral
thoracotomy with tumor weight of 2.354 mg. Tumor histopathology consisted of positive Vimentin, BCL2
and CD99 antibodies. The patient performed 3 cycles of chemotherapy after surgery using doxorubicin,
ifosfamide, and mesna. Post-chemotherapy results of CT showed metastases in the left hemidiaphragm with
an expansion of mass defects and lymphadenopathy in the upper right paratracheal.
Conclusion: The prognosis synovial sarcoma mediastinum is worse than synovial sarcoma in other organs
as seen in most recurrent cases.
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