Saw Palmetto Therapy for Lower Urinary Tract Symptoms Associated with Benign Prostatic Hyperplasia Assessment in Iraq

Abstract

Background: The current study was designed to explore the effectiveness of Saw Palmetto as monotherapy
or supplementation with tamsulosin in the treatment of patients with lower urinary tract symptoms consistent
with benign prostatic hyperplasia.
Method: The present study is diagnosed patient with moderate to severe symptomatic BPH. (60) Patients
were divided into 3 groups; Group (1) treated with Saw Palmetto cap (320 mg); Group (2) treated with
Saw Palmetto cap (320 mg) and tamsulosin (0.4mg); Group (3) treated with tamsulosin (0.4mg), daily for
3 months. The assessment is done based on the change in urological IPSS, urodynamic activity, urine flow,
voiding quantity measures, and prostate volume. Also, some measurement such as erection function, urinary
incontinence, sleeps quality, and quality of life.
Results: Saw Palmetto supplementation with tamsulosin revealed a significant decrease in the IPSS
score(P<0.01), a significant increase in the urine flow rate and the voided volume, a significant decrease
in the post-void residual volume and prostate volume (P<0.01),and decrease in serum PSA level (P<0.01).
Additionally, improved erection function decreased urinary incontinence score, improvement in sleep
quality, and improvement in the quality of life score among the Saw Palmetto supplementation group was
noticed (P?0.01).
Conclusion: The phytotherapy with saw palmetto alone or as supplement collectively produced marked
improvement in objective and subjective measurements in men with lower urinary tract symptoms consistent
with BPH: