Helicobacter Pylori Can Cause Vitamin B12 Deficiency

Abstract

Several studies have indicated that H. pylori treatment causes an impact on the status or absorption of B12 vitamin. When talking aboutmal absorption of B12 vitamin, H. pylori is a big risk, especially for adults and older people who have suffered bacteria related diseases for a long time.A literature review of more than 25 papers have found inconclusive results due to the methodological differences in them. This paper assesses the relationship among the deficiency of vitamin B12 and H. pylori.
This study involved hundred patients in total, having deficient B12 serum vitamin. The study conducted Upper G I Endoscopy and obtained gastric biopsies for histological evidence and histopathological examination of H. pylori infection.
The results of the tissue biopsy pointed out chronic antral gastritis in thirty patients and chronic atrophic gastritis in sixty-two patients. It was found that the H. pylori infection by histology is positive in eight-six patients. A significant relation was found among H. pylori and atrophic gastritis and also between B12 deficiency and H. pylori. This study concluded that, the deficiency of B12Vitamin is predominant in the Helicobacter pylori infection.