Detect the Infection with Rubella Virus and Toxoplasmosis in Pregnancy Cases Suffering from Early Abortion by Using Real Time PCR

Abstract

Congenital infections may cause fetal death or newborns with brain malformations, little information is available about the but the impact of these diseases on the outcome of pregnancy. In this study we tested the IgG and IgM antibodies for both Toxoplasma gondii and Rubella.  among 58 pregnant women with abortion. and in order to differentiate between the serological and molecular detection methods the samples were alsotested for both Toxoplasma gondii and Rubella by RT-PCR. The results showed that there is a positive relation between the infection with rubella and the infection with toxoplasma ( p=0.022, Odd= 4.9) and this co-infection attribute to abortion in women. and these results of RT-PCR were significantly different than those with ELISA test.