Histological Sections of Pancreas and Serum Biochemical Changes in Rats after Dexamethasone and Zinc Oxide Nanoparticles Injection

Abstract

Zinc Oxide Nanoparticles have been prepared using a simple green synthesis method by green tea extract (Camellia sinensis) as a reducing and capping agent, XRD measurement of Nano powder stated that Zinc Oxide had a hexagonal wurtzite structure, UV-Vis. The maximum absorption peak was approximately 318 nm and the energy gap was nearly 3.8eV calculated using Planck’s equation, blood serum sugar levels, liver function after ZnO NPs injection for rats was recorded. Forty-eight adult male rats were used and separated randomly into six groups of eight (n=8) rats in each group.Results stated that blood glucose levels, liver enzymes were increased in groups that injected by dexamethasone while considerably modified in rats administered by the first dose (100 mg/kg) of ZnO Nanoparticles while the other dose (300 mg/kg) hadn’t any significant effects.