The Role of Cytomegalovirus (CMV) and Vitamin D in Multiple Sclerosis (MS).

Abstract

Multiple sclerosis (MS) is one of the autoimmune demyelinating diseases involved in the central nervous system (CNS) and its etiological factors believed to be both environmental and genetic factors . The disease affected brain and spinal cord with various characteristic involved defect of myelination , chronic inflammation , pathological effect on axon and oligodendrocyte . The herpesvirus family is play a vital role in pathogenicity of disease . Cytomegalovirus (CMV) from these family members which detected to have a role in MS and our results investigated a significant relation of CMV with MS between patients and controls . Besides a previous data which approved the effect of the level of vitamin D on MS development and modifications in patients . In this study the results achieve significant differences in the levels of vitamin D between the two groups under study .