Prospective Clinicopathological Study of Penile Cancer Patients : A Single Institution Experience

Abstract

Background: Carcinoma of the penis is an uncommon malignancy in Western countries but constitutes a
major health problem in many countries in Asia, Africa, and South America, where it may comprise up to
10% of all malignancies.
Materials and Method: 42 consecutive patients of carcinoma penis were treated from 2013 to 2015. Clinical
and pathological profies were recorded and studied prospectively.
Results: 20/42 (48%) patients were of the age group 60 and above. majority of patients belonged to poor
socioeconomic status, 32/42 patients(76.1%). Glans of the penis was the most common site of presentation
in 28/42patients(66.6%). The most common symptoms were pus discharge from the penile ulcer in 21
patients(50%). 31/42 patients were chronic smoker or tobacco chewer. Inguinal lymph nodes were palpable
in 24/42 (57%). The most common complication associated with Groin node dissection was lymphedema in
19 patients (45.2%). 12/42 patients had inguinal lymph node metastasis in final histopathological examination
report. 50 % patients had grade II primary tumor.
Conclusion: Incidence of carcinoma penis peaks in the 6thdecade of life. Illiteracy, low socio-economic
status and phimosis appear to be main predisposing factors for carcinoma of penis. Nodal metastasis was
significantly associated with factors like T3 and high grade lesions (grade II & III). Complication rate related
to groin node dissection is high, commonest being lymphedema.