Comparison of Tuberculin Skin Test Versus Newer Quantiferon TB Gold Assay Method in Screening for Latent Tuberculosis Infection in Various High Risk Groups

Abstract

Aim: The aim of present study to evaluate the QuantiFERON-TB gold assay and tuberculin skin test to recognize tuberculosis infection amongst tuberculosis patient contact.
Methodology: A total of 55 tuberculosis patients contacts were utilized for research, blood were pinched and practices by utilizing the QuantiFERON-TB gold assay pursue by insistent management of tuberculin skin test solution in subjects forearm.All accessible associates were asked to giveblood samples for Latent tuberculosis infection intest.
Results: QuantiFERON-TB gold assay distinguishLatent tuberculosis infection with sensitivity of 88.81% and specificity of 89.9%. Tuberculin skin test: Sensitivity 67.9%, Specificity 15.9%.
Conclusion: Equallytuberculin skin test and QuantiFERON-TB gold assay can be utilized to recognize TBdisease or Latent tuberculosis infection. The present assessment of tuberculin skin test&QuantiFERON-TB gold assay consequence bears thatQFT-G assay supply additional accurate results than tuberculin skin test in revealing of Latent tuberculosis infection.