Sero Prevalence of Transfusion Transmissible Infection in Blood Donors: North Goa District Hospital Based Study

Abstract

Transfusion transmissible infections (TTIs) have emerged as one of the significant public health problems globally
in blood transfusion . The morbidity and mortality associated with TTIs have highlighted the need for improving
blood safety. The present study aims to investigate the sero prevalence of various TTIs among blood donors in the
North Goa District Hospital.
This study was a retrospective cross sectional study conducted from January 2021 upto September 2023. A total
of 5,426 blood donors were included in this study. Relevant demographic and clinical data were obtained from
the donors. Enzyme-linked immunosorbent assay (ELISA) was used to detect the presence of various TTIs such as
HIV, HBV, HCV, and Syphilis.
The mean age of the donors was 32 years, with the majority being males (87.4%). Out of the 5,426 donors, 11 tested
positive for HIV, 32 for HBV, 30 for HCV, and 1 for Syphilis. The overall sero prevalence of TTIs was found to be
1.36%.
This study highlights the importance of regular screening of blood donors to ensure blood safety. The results
of this study can be utilized to develop and implement effective donor selection strategies, which will help in
reducing the transmission of TTIs through blood transfusion.
So far no such study has been published from Goa.